View Megaloblastic Anemia Bone Marrow Pathology PNG. When such a vitamin deficiency occurs, bone… + pure red cell aplasia.
Megaloblastic anemias arise from a common defect in dna synthesis that leads to a distinctive morphological pattern within rapidly proliferating cells within the bone marrow. Bone marrow core biopsy and aspirate show hypercellular marrow with erythroid hyperplasia: Megaloblastic anemia is a type of anemia , a blood disorder in which the number of red blood cells is lower than normal.
+ increased number of megakaryocytes.
Megaloblastic anemia (ma) is a form of anemia that is caused by suppression of dna synthesis in the production of red blood cells. In the rate of deoxyribonucleic acid (dna) synthesis treatment because of ongoing rapid restoration of erythropoiesis in the bone marrow. Megaloblastic anemia, the production in the bone marrow of abnormal nucleated red cells known as megaloblasts, develops as the result of dietary deficiency of, faulty absorption of, or increased demands for vitamin b 12 or folic acid. When dna synthesis is impaired, the cell cycle cannot progress from the g2 growth stage to the mitosis (m) stage.
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